| Date | Location | Result | |
| Apr 18, 2010 | Wilson, NC | Mount Olive College 7, Pfeiffer University 2 | Box score |
| Apr 18, 2010 | Wilson, NC | Mount Olive College 5, Pfeiffer University 4 | Box score |
| Apr 17, 2010 | Wilson, NC | Pfeiffer University 8, Anderson University 5 | Box score |
| Apr 16, 2010 | Wilson, NC | Pfeiffer University 6, Erskine College 3 | Box score |
| Apr 15, 2010 | Wilson, NC | Pfeiffer University 7, Belmont Abbey 4 | Box score |
| Apr 13, 2010 | Hickory, N.C. | Pfeiffer 19, Lenoir-Rhyne 9 | Box score |
| Apr 11, 2010 | Anderson, S.C. | Anderson Trojans 3, Pfeiffer 1 | Box score |
| Apr 10, 2010 | Andderson, S.C. | Pfeiffer 7, Anderson Trojans 2 | Box score |
| Apr 10, 2010 | Anderson,S.C. | Anderson Trojans 13, Pfeiffer 12 | Box score |
| Apr 07, 2010 | Misenheimer, NC | Pfeiffer 6, Lander 4 | Box score |
| Apr 06, 2010 | Pembroke, NC | Armstrong Atlantic 6, Pfeiffer 1 | Box score |
| Apr 03, 2010 | Laurinburg, N.C. | Pfeiffer 12, St. Andrews 4 | Box score |
| Apr 02, 2010 | Laurinburg, N.C. | St. Andrews 6, Pfeiffer 5 | Box score |
| Apr 02, 2010 | Laurinburg, N.C. | Pfeiffer 14, St. Andrews 4 | Box score |
| Mar 31, 2010 | Jefferson City, Tenn | Pfeiffer 15, Carson-Newman 12 | Box score |
| Mar 30, 2010 | Greeneville, Tenn. | Tusculum 27, Pfeiffer 7 | Box score |
| Mar 27, 2010 | Due West, SC | Pfeiffer University 6, Erskine College 4 | Box score |
| Mar 27, 2010 | Due West, SC | Erskine College 5, Pfeiffer University 4 | Box score |
| Mar 26, 2010 | Due West, SC | Erskine College 8, Pfeiffer University 6 | Box score |
| Mar 24, 2010 | Misenheimer, NC | Pfeiffer 9, Georgia College & St 8 | Box score |
| Mar 23, 2010 | Misenheimer, NC | Georgia College & St 8, Pfeiffer 5 | Box score |
| Mar 21, 2010 | Misenheimer, NC | Pfeiffer 10, Limestone 1 | Box score |
| Mar 20, 2010 | Misenheimer, NC | Pfeiffer 3, Limestone 2 | Box score |
| Mar 20, 2010 | Misenheimer, NC | Pfeiffer 6, Limestone 5 | Box score |
| Mar 17, 2010 | Pembroke, N.C. | UNC Pembroke 11, Pfeiffer 7 | Box score |
| Mar 16, 2010 | Misenheimer, NC | Francis Marion Univ. 11, Pfeiffer 3 | Box score |
| Mar 13, 2010 | Misenheimer, NC | Pfeiffer 16, Post 3 | Box score |
| Mar 13, 2010 | Misenheimer, NC | Post 17, Pfeiffer 8 | Box score |
| Mar 12, 2010 | Misenheimer, NC | Pfeiffer 15, Post 4 | Box score |
| Mar 10, 2010 | Aiken, SC | USC Aiken 10, Pfeiffer 5 | Box score |
| Mar 09, 2010 | Mars Hill, N.C. | Pfeiffer 19, Mars Hill 15 | Box score |
| Mar 07, 2010 | Misenheimer, NC | Mount Olive 14, Pfeiffer 9 | Box score |
| Mar 06, 2010 | Misenheimer, NC | Pfeiffer 7, Mount Olive 6 | Box score |
| Mar 06, 2010 | Misenheimer, NC | Mount Olive 10, Pfeiffer 7 | Box score |
| Mar 04, 2010 | Misenheimer, NC | Lander 14, Pfeiffer 5 | Box score |
| Mar 01, 2010 | Misenheimer, NC | Pfeiffer 14, Lake Erie 3 | Box score |
| Feb 28, 2010 | Misenheimer, NC | Pfeiffer 16, Coker 10 | Box score |
| Feb 27, 2010 | Misenheimer, NC | Pfeiffer 8, Coker 6 | Box score |
| Feb 27, 2010 | Misenheimer, NC | Coker 8, Pfeiffer 4 | Box score |
| Feb 25, 2010 | Misenheimer, NC | UNC-Pembroke 12, Pfeiffer 11 | Box score |
| Feb 23, 2010 | Misenheimer, NC | Pfeiffer 22, Tusculum 6 | Box score |
| Feb 21, 2010 | Belmont, NC | Belmont Abbey 12, Pfeiffer 8 | Box score |
| Feb 20, 2010 | Belmont, NC | Pfeiffer 8, Belmont Abbey 4 | Box score |
| Feb 20, 2010 | Belmont, NC | Pfeiffer 9, Belmont Abbey 3 | Box score |
| Feb 17, 2010 | Misenheimer, NC | Carson-Newman 17, Pfeiffer 7 | Box score |
| Feb 16, 2010 | Misenheimer, NC | Catawba 7, Pfeiffer 6 | Box score |
| Feb 15, 2010 | Misenheimer, NC | Pfeiffer 5, Barton 2 | Box score |
| Feb 14, 2010 | Misenheimer, NC | Barton 3, Pfeiffer 1 | Box score |
| Feb 14, 2010 | Misenheimer, NC | Barton 5, Pfeiffer 4 | Box score |
| Feb 10, 2010 | Florence, SC | Francis Marion Univ. 8, Pfeiffer University 5 | Box score |
| Feb 07, 2010 | Dahlonega, GA | Pfeiffer 6, North Georgia 4 | Box score |
| Feb 07, 2010 | Dahlonega, GA | Pfeiffer 7, North Georgia 6 | Box score |
| Feb 06, 2010 | Dahlonega, GA | North Georgia 11, Pfeiffer 3 | Box score |
| Feb 04, 2010 | Salisbury,NC | Catawba 10, Pfeiffer 6 | Box score |